This invention provides an improved method for producing a novel interfacing capillary device that is less costly and more durable than existing sheathless devices. This simplified production method does not require sample dilution, etching, or precision hand tools, and is automated and reproducible.
The Surface Modified Ceramic Filter (SMCF) provides an inexpensive gravity filtration device for the removal of inorganic chemicals, organic chemicals, and pathogens from water. The surface modification is easily incorporated into traditional ceramic production methods, making this filter ideal for both industrial mass-production and remote operations in developing countries.
The invention provides a "sample-in-answer-out" microfluidic exosome profiling platform which integrates immunoaffinity isolation of plasma exosomes with quantitative detection of both surface and intravesicular markers for characterization of exosomal phenotypes.
The invention entails solution conditions that can prolong the recovery and foldability of proteins under non-denaturing conditions in the presence of the tetradecameric GroEL chaperonin.