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The invention describes CD44-selective nanovector systems for cancer-targeted delivery of molecular therapeutics.

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Broad based label-free systems identify protein stabilizers at physiological or near physiological conditions that specifically inhibit Bacterial Toxin or Viral entry into cells. 

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This invention is a tubular electrospun scaffold of natural protein gelatin and synthetic polyglycolic acid (PGA) / poly-lactic-co-glycolic (PLGA) polymers in a bioreactor system connected to a flow circuit and seeded with cultured fibroblasts and endothelial cells.

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Our researcher at KUMC has developed methods of prediction, diagnosis, and treatment of primary osteoarthritis.

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The invention consists of new bi-functional protein inhibitors (“BPIs”) for treatment and diagnostics of autoimmune diseases such as MS and experimental autoimmune encephalomyelitis.  The novel BPIs are capable of modulating the immune response towards a TH2 response.

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Transmission of blood-borne infections (e.g., HIV) from health care exposures was previously believed to be uncommon. However, multiple outbreaks across the U.S. over the last several years have shed light on this problem. Thousands of individuals exposed to potential blood-borne pathogens. As recently as October 2009, in one of the hospitals in Florida, the nurse routinely used the same bag of saline on multiple patients. In another outbreak in an outpatient oncology clinic in Nebraska, the nurse would reuse a syringe to perform a saline flush. Saline for multiple patients was acquired from a common bag. More than 600 patients were notified and 99 patients were diagnosed with Hepatitis C. These cases all have in common acquisition of saline or a drug from a common container via a contaminated needle and/or syringe. Despite the increasing use of single-dose vials, such outbreaks occur as providers still use these single-dose vials on multiple individuals to reduce costs.  

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The VestibuGLIDE System represents a new medical device designed to provide therapeutic stimulation of the vestibular system in premature infants.

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A novel thin-film single-offset superlattice photovoltaic technology with superior performance and low fabrication cost through use of pulsed laser deposition (PLD) manufacturing methods and lower cost materials.

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Immuno-oncology represents the new wave of personalized medicine. Scientists at the University of Kansas have developed an innovative approach to activate intracellular signaling pathways that enhance T cell activation, expansion, and differentiation.

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The proposed technology offers a new method to improve homing of umbilical cord blood (UCB) to bone marrow during hematopoietic stem cell (HSC) transplantation in a safe, highly efficacious, and cost-effective way.

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