All Available Technologies
The technology presents a novel structural modification of an existing first generation Grp94 selective inhibitor to generate a second generation Grp94-specific scaffold which has greater affinity and selectivity compared to existing inhibitors and prevents unfavorable binding of other Hsp90 isoforms.
Unique chemical derivatives invented by University of Kansas (KU) researchers that could be used to detect inhibitors of cellular efflux transporters and other agents.
This invention presents a novel series of modified cephalosporins, which exclusively target non-replicating mycobacterium tuberculosis.
The developed technology aims to solve the water production and management problem in the cathode catalyst layer of a PEM Fuel Cell during a high current density operation.
Continuous process for the controlled ozonolysis of organsolv lignin in a solvent consisting of short chain carboxylic acids or short chain carboxylic acid/water mixtures to yield aromatic monomer products including vanillin.
This invention allows use of an efficient and stable oxygen evolution catalyst that facilitates water splitting without requiring noble metals or complicated synthesis methods.
A safe method for the direct oxidation of methane and light alkanes to methanol and other oxygenates is disclosed. Selective catalytic oxidation can be a transformative technology for using increasing abundant natural gas, bio-gas and other sources of low value hydrocarbons via gas to liquid process.
The present invention provides decellularized cartilage (DCC) fragments or powder as a raw material component to be utilized for scaffolds and provides a microenvironment similar to that of native cartilage tissue. The DCC powder provides a platform technology upon which many cartilage, or even bone, tissue engineering scaffolds could be based.
A device for rapid dialysis of microliter volume liquid samples useful in laboratory-scale dialysis operations.
Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications. These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.